概述

  • 产品名称Anti-EPS8抗体
    参阅全部 EPS8 一抗
  • 描述
    小鼠多克隆抗体to EPS8
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human EPS8 (NP_004438.3, amino acids 1-822)

  • 阳性对照
    • Human liver tissue lysate, K562 cell lysate, EPS8 transfected 293T cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: Whole serum
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab89477 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 92 kDa.

靶标

  • 功能Upon binding to EGF receptor enhances EGF-dependent mitogenic signals. Can bind multiple cellular targets.
  • 组织特异性Expressed in all tissues analyzed, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed in all epithelial and fibroblastic lines examined and in some, but not all, hematopoietic cells.
  • 序列相似性Belongs to the EPS8 family.
    Contains 1 PH domain.
    Contains 1 SH3 domain.
  • 结构域The SH3 domain mediates interaction with SHB.
  • 翻译后修饰Phosphorylated by several receptor tyrosine kinases.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Epidermal growth factor receptor kinase substrate 8 antibody
    • Epidermal growth factor receptor pathway substrate 8 antibody
    • EPS 8 antibody
    • EPS8 antibody
    • EPS8_HUMAN antibody
    see all

Anti-EPS8 antibody 图像

  • Anti-EPS8 antibody (ab89477) at 1/500 dilution + Human liver tissue lysate at 50 µg

    Predicted band size : 92 kDa
    Observed band size : 92 kDa
  • Anti-EPS8 antibody (ab89477) at 1/500 dilution + K-562 cell lysate at 50 µg

    Predicted band size : 92 kDa
  • All lanes : Anti-EPS8 antibody (ab89477) at 1/500 dilution

    Lane 1 : EPS8 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 92 kDa
    Observed band size : 100 kDa (why is the actual band size different from the predicted?)

Anti-EPS8 antibody (ab89477)参考文献

ab89477 has not yet been referenced specifically in any publications.

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