Anti-EPS15R抗体- Aminoterminal end (ab71728)

概述

  • 产品名称Anti-EPS15R抗体- Aminoterminal end
    参阅全部 EPS15R 一抗
  • 描述
    兔多克隆抗体to EPS15R - Aminoterminal end
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the N terminal region of human EPS15R.

  • 阳性对照
    • Y79 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab71728 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 104 kDa (predicted molecular weight: 94 kDa).

靶标

  • 功能Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
  • 序列相似性Contains 1 EF-hand domain.
    Contains 3 EH domains.
  • 翻译后修饰Phosphorylated on tyrosine residues by EGFR.
  • 细胞定位Cell membrane. Nucleus. Membrane > coated pit. Localized to plasma membrane coated pits.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EP15R_HUMAN antibody
    • epidermal growth factor receptor pathway substrate 15- ike 1 antibody
    • Epidermal growth factor receptor substrate 15 like 1 antibody
    • Epidermal growth factor receptor substrate 15-like 1 antibody
    • epidermal growth factor receptor substrate EPS15R antibody
    • Eps15 related protein antibody
    • Eps15-related protein antibody
    • EPS15L1 antibody
    • Eps15R antibody
    see all

Anti-EPS15R antibody - Aminoterminal end 图像

  • Anti-EPS15R antibody - Aminoterminal end (ab71728) at 1/100 dilution + Y79 cell lysate at 12.5 µg

    Predicted band size : 94 kDa
    Observed band size : 104 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 40 kDa,50 kDa. We are unsure as to the identity of these extra bands.

Anti-EPS15R antibody - Aminoterminal end (ab71728)参考文献

ab71728 has not yet been referenced specifically in any publications.

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