Anti-EPS15抗体- C-terminal (ab71272)

概述

  • 产品名称Anti-EPS15抗体- C-terminal
    参阅全部 EPS15 一抗
  • 描述
    兔多克隆抗体to EPS15 - C-terminal
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide selected from the C-terminal region of human EPS15 conjugated to KLH.

  • 阳性对照
    • HL60 cell line lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab71272 is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab71272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 99 kDa (predicted molecular weight: 99 kDa).
ELISA 1/1000.

靶标

  • 相关性The eps15 protein (EGFR pathway substrate clone 15) is tyrosine phosphorylated by the activation of the EGF and PDGF receptors. It was first identified as an 896 amino acid protein in mouse. Subsequent cloning of the human protein showed 90% homology to the mouse form. Several physiological functions have been proposed for eps15. Phosphorylation by EGF and PDGF receptors indicates that eps15 plays a role in signal transduction, cell proliferation and endocytosis.
  • 细胞定位Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Recruited to the plasma membrane upon EGFR activation and localizes to coated pits.
  • 数据库链接
  • 别名
    • AF 1P antibody
    • AF 1p protein antibody
    • AF1P antibody
    • ALL1 fused gene from chromosome 1 antibody
    • Epidermal growth factor receptor pathway substrate 15 antibody
    • Epidermal growth factor receptor substrate 15 antibody
    • EPS 15 antibody
    • MLLT 5 antibody
    • MLLT5 antibody
    • Protein Eps 15 antibody
    • Protein Eps15 antibody
    see all

Anti-EPS15 antibody - C-terminal 图像

  • Anti-EPS15 antibody - C-terminal (ab71272) at 1/100 dilution + HL60 cell line lysate at 35 µg

    Predicted band size : 99 kDa
    Observed band size : 99 kDa
    Additional bands at : 72 kDa. We are unsure as to the identity of these extra bands.

Anti-EPS15 antibody - C-terminal (ab71272)参考文献

ab71272 has not yet been referenced specifically in any publications.

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