概述

  • 产品名称Anti-EPS15抗体
    参阅全部 EPS15 一抗
  • 描述
    兔多克隆抗体to EPS15
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Rhesus monkey, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between residue 575 and 625 of human EPS15 (NP_001972.1).

  • 阳性对照
    • Human Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Ovarian Carcinoma, Pancreatic Islet Cell Tumor, Prostate Carcinoma and Testicular Seminoma tissues.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性The eps15 protein (EGFR pathway substrate clone 15) is tyrosine phosphorylated by the activation of the EGF and PDGF receptors. It was first identified as an 896 amino acid protein in mouse. Subsequent cloning of the human protein showed 90% homology to the mouse form. Several physiological functions have been proposed for eps15. Phosphorylation by EGF and PDGF receptors indicates that eps15 plays a role in signal transduction, cell proliferation and endocytosis.
    • 细胞定位Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Recruited to the plasma membrane upon EGFR activation and localizes to coated pits.
    • 数据库链接
    • 别名
      • AF 1P antibody
      • AF 1p protein antibody
      • AF1P antibody
      • ALL1 fused gene from chromosome 1 antibody
      • Epidermal growth factor receptor pathway substrate 15 antibody
      • Epidermal growth factor receptor substrate 15 antibody
      • EPS 15 antibody
      • MLLT 5 antibody
      • MLLT5 antibody
      • Protein Eps 15 antibody
      • Protein Eps15 antibody
      see all

    Anti-EPS15 antibody 图像

    • ab84810, at 1/100 dilution, staining EPS15 in formalin-fixed, paraffin-embedded human testicular seminoma by Immunohistochemistry using a Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Hilyte PlusTM 555 secondary antibody at a dilution of 1/100.
    • ab84810, at 1/500 dilution, staining EPS15 in formalin-fixed, paraffin-embedded human testicular seminoma by Immunohistochemistry using DAB staining.
    • ab84810, at 1/500 dilution, staining EPS15 in formalin-fixed, paraffin-embedded human prostate carcinoma by Immunohistochemistry using DAB staining.

    Anti-EPS15 antibody (ab84810)参考文献

    ab84810 has not yet been referenced specifically in any publications.

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