概述

  • 产品名称Anti-EPR1抗体
  • 描述
    兔多克隆抗体to EPR1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    This antibody was generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human EPR1.

  • 阳性对照
    • HL60 cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明This antibody was purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

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应用

Our Abpromise guarantee covers the use of ab38876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa).
ELISA 1/1000.

靶标

  • 相关性Cellular receptors for blood proteases regulate chemotaxis, extracellular proteolysis, and growth behavior of normal and malignant cells. Effector cell protease receptor-1 (EPR1) is a receptor for the coagulation protease factor Xa. EPR1 is characterized by a cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich cytoplasmic tail featuring at least 15 potential phosphorylation sites. EPR1 also contains 2 N-linked glycosylation sites, 4 O-linked glycosylation sites, and a chondroitin sulfate attachment site, which may provide anchoring for carbohydrate chains, EPR1 transfectants bind to factor Xa in a specific and saturable manner, and in the absence of factor V/Va promote prothrombin activation in a factor Xa concentration-dependent reaction. Activated platelets and megakaryocytes express EPR1. Both EPR1 and membrane-bound factor Va are thought to be required to mediate factor Xa binding to the activated platelet to form a functional prothrombinase complex.
  • 数据库链接
  • 别名
    • Effector cell peptidase receptor 1 antibody
    • Effector cell protease receptor 1 antibody
    • EPR 1 antibody

Anti-EPR1 antibody 图像

  • Anti-EPR1 antibody (ab38876) at 1/100 dilution + HL60 cell lysate

    Predicted band size : 37 kDa
    Observed band size : 37 kDa

Anti-EPR1 antibody (ab38876)参考文献

ab38876 has not yet been referenced specifically in any publications.

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