概述

  • 产品名称Anti-Epoxide hydrolase抗体
    参阅全部 Epoxide hydrolase 一抗
  • 描述
    兔多克隆抗体to Epoxide hydrolase
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Pig
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 1-193 of Human Epoxide hydrolase (NP_000111).

  • 阳性对照
    • WB: 293T, HeLa and HepG2 cell lysates ICC/IF: Hela cells IHC-P: SG xenograft

性能

应用

Our Abpromise guarantee covers the use of ab96695 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 53 kDa.
IHC-P 1/100 - 1/500.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
  • 组织特异性Found in liver.
  • 疾病相关Note=In some populations, the high activity haplotype tyr113/his139 is overrepresented among women suffering from pregnancy-induced hypertension (pre-eclampsia) when compared with healthy controls.
    Defects in EPHX1 are a cause of familial hypercholanemia (FHCA) [MIM:607748]. FHCA is a disorder characterized by elevated serum bile acid concentrations, itching, and fat malabsorption.
  • 序列相似性Belongs to the peptidase S33 family.
  • 细胞定位Microsome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EPHX 1 antibody
    • EPHX antibody
    • Ephx1 antibody
    • EPOX antibody
    • Epoxide hydratase antibody
    • Epoxide hydrolase 1 antibody
    • Epoxide hydrolase 1 microsomal (xenobiotic) antibody
    • Epoxide hydroxylase 1 antibody
    • Epoxide hydroxylase 1 microsomal (xenobiotic) antibody
    • HYEP_HUMAN antibody
    • HYL1 antibody
    • MEH antibody
    • Microsomal epoxide hydrolase antibody
    see all

Anti-Epoxide hydrolase antibody 图像

  • All lanes : Anti-Epoxide hydrolase antibody (ab96695) at 1/1000 dilution

    Lane 1 : HeLa whole cell lysate
    Lane 2 : HepG2 whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 53 kDa
  • ab96695, at a 1/200 dilution, staining Epoxide hydrolase in methanol fixed HeLa cells by Immunofluorescence analysis. Lower image costained with Hoerchst 33342.
  • ab96695, at a 1/500 dilution, staining Epoxide hydrolase in paraffin embedded SG xenograft by Immunohistochemical analysis.

Anti-Epoxide hydrolase antibody (ab96695)参考文献

This product has been referenced in:
  • O'Shaughnessy PJ  et al. Maternal smoking and fetal sex significantly affect metabolic enzyme expression in the human fetal liver. J Clin Endocrinol Metab 96:2851-60 (2011). WB ; Human . Read more (PubMed: 21715529) »

See 1 Publication for this product

Product Wall

Thank you very much for your interest in ab96695. To our knowledge, ab96695 has not been tested in mouse or rat . Therefore, I can offer a discount off a future purchase if you buy ab96695 now, test it in mouse or rat and submit feedback to us in the f...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"