概述

  • 产品名称
  • 描述
    兔多克隆抗体to EPHX2
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH-conjugated synthetic peptide from an internal domain of Human EPHX2

  • 阳性对照
    • Human kidney tissue

应用

Our Abpromise guarantee covers the use of ab115284 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 20 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    Acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. Has low phosphatase activity.
  • 序列相似性
    Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
  • 结构域
    The N-terminal domain has phosphatase activity. The C-terminal domain has epoxide hydrolase activity.
  • 翻译后修饰
    The N-terminus is blocked.
    The covalent modification of cysteine by 15-deoxy-Delta12,14-prostaglandin-J2 is autocatalytic and reversible. It may occur as an alternative to other cysteine modifications, such as S-nitrosylation and S-palmitoylation.
  • 细胞定位
    Cytoplasm. Peroxisome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Bifunctional epoxide hydrolase 2 antibody
    • CEH antibody
    • Cytosolic epoxide hydrolase antibody
    • EPHX2 antibody
    • Epoxide hydratase antibody
    • Epoxide hydrolase 2 antibody
    • Epoxide hydrolase 2 cytoplasmic antibody
    • epoxide hydrolase 2, cytosolic antibody
    • Epoxide hydrolase soluble antibody
    • HYES_HUMAN antibody
    • SEH antibody
    • Soluble epoxide hydrolase antibody
    see all

图片

  • Human kidney formalin-fixed, paraffin-embedded tissue stained with ab115284 at 20 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

文献

ab115284 has not yet been referenced specifically in any publications.

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