概述

  • 产品名称Anti-Ephrin B2抗体
    参阅全部 Ephrin B2 一抗
  • 描述
    山羊多克隆抗体to Ephrin B2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Chicken, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide:

    CPKVDSKTVGQYE

    , corresponding to internal sequence amino acids 62-74 of Human Ephrin B2 (NP_004084.1).

  • 阳性对照
    • Human, Mouse and Rat Lung lysates

性能

应用

Our Abpromise guarantee covers the use of ab104942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 35 kDa (predicted molecular weight: 37 kDa).

靶标

  • 功能Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.
    (Microbial infection) Acts as a receptor for Hendra virus and Nipah virus.
  • 组织特异性Lung and kidney.
  • 序列相似性Belongs to the ephrin family.
    Contains 1 ephrin RBD (ephrin receptor-binding) domain.
  • 翻译后修饰Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EFN B2 antibody
    • EFNB 2 antibody
    • Efnb2 antibody
    • EFNB2_HUMAN antibody
    • Eph related receptor tyrosine kinase ligand 5 antibody
    • EPH-related receptor tyrosine kinase ligand 5 antibody
    • ephrin B2 antibody
    • Ephrin-B2 antibody
    • EphrinB2 antibody
    • EPLG 5 antibody
    • EPLG5 antibody
    • Htk L antibody
    • HTK ligand antibody
    • HTK-L antibody
    • HTKL antibody
    • LERK 5 antibody
    • LERK-5 antibody
    • LERK5 antibody
    • Ligand of eph related kinase 5 antibody
    • MGC126226 antibody
    • MGC126227 antibody
    • MGC126228 antibody
    • OTTMUSP00000024973 antibody
    see all

Anti-Ephrin B2 antibody 图像

  • Anti-Ephrin B2 antibody (ab104942) at 0.1 µg/ml + Rat lung lysate (in RIPA buiffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 37 kDa

Anti-Ephrin B2 antibody (ab104942)参考文献

ab104942 has not yet been referenced specifically in any publications.

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