Anti-Ephrin B (phospho Y329)抗体(ab111487)

概述

  • 产品名称Anti-Ephrin B (phospho Y329)抗体
    参阅全部 Ephrin B 一抗
  • 描述
    兔多克隆抗体to Ephrin B (phospho Y329)
  • 特异性ab111487 detects endogenous levels of Ephrin B only when phosphorylated at tyrosine 329 (Human: Tyr329/316; Mouse: Tyr318/319; Rat: Tyr328/-).
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic phosphopeptide derived from Human Ephrin B around the phosphorylation site of tyrosine 329 (P-V-YP-I-V).

  • 阳性对照
    • Human brain tissue

性能

应用

Our Abpromise guarantee covers the use of ab111487 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 相关性Ephrin B proteins are thought to play key roles in cellular functions as diverse as neuronal migration and blood vessel development. Ephrin B molecules expressed at the membrane surface bind to the Ephrin B family receptors on target cells during cell to cell contact. This interaction leads to cell signaling in the target cell but also generates a reverse signal in the cell expressing Ephrin B on its surface. This reverse signaling event is thought to be critical for vessel maturation and neuronal development. Importantly, tyrosine phosphorylation of Ephrin B is thought to be a critical component of this reverse signaling event. Recent work demonstrated that Tyr331 of Ephrin B was phosphorylated in HEK293 cells after stimulation by the soluble Ephrin B2 receptor tyrosine kinase.
  • 细胞定位Membrane; single pass type I membrane protein.
  • 数据库链接
  • 别名
    • CEK5 ligand antibody
    • EFNB1 antibody
    • ELK L antibody
    • ELK ligand antibody
    • ELKL antibody
    • EPH related receptor tyrosine kinase ligand 2 antibody
    • Ephrin B1 antibody
    • Ephrin B2 antibody
    • LERK2 antibody
    see all

Anti-Ephrin B (phospho Y329) antibody 图像

  • ab111487, at 1/50 dilution, staining Ephrin B in paraffin-embedded Human brain tissue by Immunohistochemistry, in the presence (right panel) or absence (left panel) of immunising peptide.

Anti-Ephrin B (phospho Y329) antibody (ab111487)参考文献

ab111487 has not yet been referenced specifically in any publications.

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