Anti-Eph receptor B1 + Eph receptor B2抗体(ab61765)
Key features and details
- Rabbit polyclonal to Eph receptor B1 + Eph receptor B2
- Suitable for: IHC-P, WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Eph receptor B1 + Eph receptor B2抗体
参阅全部 Eph receptor B1 + Eph receptor B2 一抗 -
描述
兔多克隆抗体to Eph receptor B1 + Eph receptor B2 -
宿主
Rabbit -
经测试应用
适用于: IHC-P, WB, ICC/IFmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic non-phosphopeptide derived from human Eph receptor B1 from around the phosphorylation site of tyrosine 594 (K-I-YP-I-D).
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阳性对照
- Extracts from HepG2 cells, HuvEc cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab61765于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/50 - 1/100.
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WB |
1/500 - 1/1000. Detects a band of approximately 110 kDa (predicted molecular weight: 110 kDa).
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ICC/IF |
1/500 - 1/1000.
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说明 |
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IHC-P
1/50 - 1/100. |
WB
1/500 - 1/1000. Detects a band of approximately 110 kDa (predicted molecular weight: 110 kDa). |
ICC/IF
1/500 - 1/1000. |
靶标
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相关性
Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor. -
细胞定位
Membrane; Single-pass type I membrane protein. -
数据库链接
- Entrez Gene: 2047 Human
- Entrez Gene: 2048 Human
- Entrez Gene: 13844 Mouse
- Entrez Gene: 270190 Mouse
- Entrez Gene: 24338 Rat
- Entrez Gene: 313633 Rat
- Omim: 600600 Human
- Omim: 600997 Human
see all -
别名
- EPH B1 antibody
- EPH B2 antibody
- Eph tyrosine kinase 2 antibody
see all
图片
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HuvEc cells stained wth ab61765 at 1/500 - 1/1000, with and without the immunising peptide.
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All lanes : Anti-Eph receptor B1 + Eph receptor B2 antibody (ab61765) at 1/500 dilution
Lane 1 : Extracts from HepG2 cells.
Lane 2 : Extracts from HepG2 cells and the immunising peptide.
Predicted band size: 110 kDa
Observed band size: 110 kDa -
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using EPHB1/2 Antibody. The picture on the right is blocked with the synthesized peptide.
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab61765 被引用在 1 文献中.
- Li L et al. Prognostic values of EphB1/B2 and p-EphB1/B2 expression in non-small cell lung cancer. Int J Clin Exp Pathol 10:10092-10101 (2017). PubMed: 31966900