Anti-Eph receptor A3抗体[RM-0052-7C13] (ab73255)

概述

• 产品名称
  Anti-Eph receptor A3抗体[RM-0052-7C13]
  参阅全部 Eph receptor A3 一抗
• 描述
  大鼠单克隆抗体[RM-0052-7C13] to Eph receptor A3
• 特异性
  ab73255 is specific for mouse Eph receptor A3. It does not cross react with recombinant mouse Eph receptors A2, A4, A6, A7, A8 and B2, B3 or B6.
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Mouse
  
• 免疫原

  Recombinant mouse Eph receptor A3 extracellular domain

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• 存储溶液
  Preservative: None
  Constituents: PBS
• Concentration information loading...
• 纯度
  Immunogen affinity purified
• 纯化说明
  ab73255 was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with recombinant mouse Eph receptor A3 extracellular domain. The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from a 0.2 µm filtered solution,
• 克隆
  单克隆
• 克隆编号
  RM-0052-7C13
• 同种型
  IgG2
• 研究领域
  • Cardiovascular
  • Angiogenesis
  • Ephrins
  • Eph Receptors

  • Neuroscience
  • Neurotransmission
  • Intracellular Signaling
  • Kinases

  • Neuroscience
  • Cell Type Marker
  • Neuron marker
  • Growth Cone

  • Signal Transduction
  • Protein Phosphorylation
  • Tyrosine Kinases
  • Receptor Tyrosine Kinases

  • Neuroscience
  • Neurology process
  • Growth and Development
  • Axonal Guidance Proteins

  • Neuroscience
  • Neurotransmission
  • Receptors / Channels
  • Tyrosine Kinase Receptors

相关产品

• Compatible Secondaries
  • Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
  • Goat Anti-Rat IgG H&L (HRP) (ab205720)

应用

靶标

• 功能
  Receptor for members of the ephrin-A family. Binds to ephrin-A2, -A3, -A4 and -A5. Could play a role in lymphoid function.
• 组织特异性
  Widely expressed. Highest level in placenta.
• 疾病相关
  Defects in EPHA3 may be a cause of colorectal cancer (CRC) [MIM:114500].
• 序列相似性
  Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
  Contains 2 fibronectin type-III domains.
  Contains 1 protein kinase domain.
  Contains 1 SAM (sterile alpha motif) domain.
• 细胞定位
  Secreted and Cell membrane.

• Target information above from: UniProt accession P29320 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 13837 Mouse
  • SwissProt: P29319 Mouse
  • Unigene: 1977 Mouse
• 别名
  • AW492086 antibody
  • Cek4 antibody
  • EC 2.7.10.1 antibody

  • EK4 antibody
  • End3 antibody
  • Eph receptor A3 antibody
  • EPH-like kinase 4 antibody
  • EPH-like tyrosine kinase 1 antibody
  • EPHA3 antibody
  • EPHA3_HUMAN antibody
  • Ephrin receptor EphA3 antibody
  • Ephrin type-A receptor 3 antibody
  • ETK 1 antibody
  • ETK antibody
  • ETK1 antibody
  • HEK 4 antibody
  • HEK antibody
  • HEK4 antibody
  • Human embryo kinase 1 antibody
  • Human embryo kinase antibody
  • Mek4 antibody
  • MGC109882 antibody
  • Receptor tyrosine kinase HEK antibody
  • Testicular tissue protein Li 64 antibody
  • Tyro 4 antibody
  • Tyro4 antibody
  • TYRO4 protein tyrosine kinase antibody
  • Tyrosine protein kinase receptor ETK 1 antibody
  • Tyrosine-protein kinase receptor ETK1 antibody
  • Tyrosine-protein kinase TYRO4 antibody

  see all

实验方案

• Western blot protocols