RabMAb

Anti-Eotaxin抗体[EPR5824] (ab125018)

概述

  • 产品名称Anti-Eotaxin抗体[EPR5824]
    参阅全部 Eotaxin 一抗
  • 描述
    兔单克隆抗体[EPR5824] to Eotaxin
  • 经测试应用适用于: WBmore details
    不适用于: IHC-P or IP
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human Eotaxin.

  • 阳性对照
    • Eotaxin recombinant protein.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 解离常数(KD KD = 8.80 x 10 -11 M Learn more about KD
  • 存储溶液pH: 7.20
    Preservative: 0.01% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
  • 纯度Tissue culture supernatant
  • 克隆单克隆
  • 克隆编号EPR5824
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab125018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 8 kDa (predicted molecular weight: 11 kDa). Tested using the recombinant protein.
  • 应用说明Is unsuitable for IHC-P or IP.
  • 靶标

    • 功能In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
    • 序列相似性Belongs to the intercrine beta (chemokine CC) family.
    • 翻译后修饰O-linked glycan consists of a Gal-GalNAc disaccharide which is mofified with up to 2 sialic acid residues.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C-C motif chemokine 11 antibody
      • CCL 11 antibody
      • CCL11 antibody
      • CCL11_HUMAN antibody
      • chemokine (C-C motif) ligand 11 antibody
      • Chemokine C C motif ligand 11 antibody
      • Chemokine CC Motif Ligand 11 antibody
      • Chemokine ligand 11 antibody
      • Eosinophil chemotactic protein antibody
      • Eotaxin antibody
      • eotaxin-1 antibody
      • MGC22554 antibody
      • SCYA 11 antibody
      • SCYA11 antibody
      • Small inducible cytokine A11 antibody
      • Small inducible cytokine subfamily A (Cys Cys) member 11 antibody
      • small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin) antibody
      • Small inducible cytokine subfamily A member 11 antibody
      • Small-inducible cytokine A11 antibody
      see all

    Anti-Eotaxin antibody [EPR5824] 图像

    • Anti-Eotaxin antibody [EPR5824] (ab125018) at 1/1000 dilution + Eotaxin recombinant protein at 0.01 µg

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 11 kDa
      Observed band size : 8 kDa (why is the actual band size different from the predicted?)
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-Eotaxin antibody [EPR5824] (ab125018)参考文献

    ab125018 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"