概述

  • 产品名称
    Anti-ENTPD5抗体[EPR3783]
    参阅全部 ENTPD5 一抗
  • 描述
    兔单克隆抗体[EPR3783] to ENTPD5
  • 经测试应用
    适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • Human fetal liver, Hela and LNCaP lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab92542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/5000. Predicted molecular weight: 47 kDa.
  • 应用说明
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能
      Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
    • 组织特异性
      Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues.
    • 通路
      Protein modification; protein glycosylation.
    • 序列相似性
      Belongs to the GDA1/CD39 NTPase family.
    • 翻译后修饰
      N-glycosylated; high-mannose type.
    • 细胞定位
      Endoplasmic reticulum lumen.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CD39 like 4 antibody
      • AI196558 antibody
      • AI987697 antibody
      • CD39 antigen like 4 antibody
      • CD39 antigen-like 4 antibody
      • CD39 like 4 antibody
      • CD39L4 antibody
      • Ectonucleoside triphosphate diphosphohydrolase 5 antibody
      • ENTP5_HUMAN antibody
      • Entpd5 antibody
      • ER UDPase antibody
      • ER-UDPase antibody
      • GDPase ENTPD5 antibody
      • Guanosine-diphosphatase ENTPD5 antibody
      • MGC163357 antibody
      • MGC163359 antibody
      • mNTPase antibody
      • NTPDase 5 antibody
      • Nucleoside diphosphatase antibody
      • PCPH antibody
      • Pcph proto oncogene protein antibody
      • Proto oncogene CPH antibody
      • UDPase ENTPD5 antibody
      • Uridine-diphosphatase ENTPD5 antibody
      see all

    图片

    • All lanes : Anti-ENTPD5 antibody [EPR3783] (ab92542) at 1/1000 dilution

      Lane 1 : Human fetal liver lysate
      Lane 2 : Hela cell lysate
      Lane 3 : LNCaP cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP conjugated Goat anti-Rabbit IgG at 1/2000 dilution

      Predicted band size : 47 kDa

    实验方案

    文献

    This product has been referenced in:
    • Shelton LM  et al. Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney. Kidney Int 88:1261-1273 (2015). WB ; Mouse . Read more (PubMed: 26422507) »

    See 1 Publication for this product

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    There are currently no Customer reviews or Questions for ab92542.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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