概述

  • 产品名称Anti-ENTPD5抗体
    参阅全部 ENTPD5 一抗
  • 描述
    兔多克隆抗体to ENTPD5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant protein fragment containing a sequence corresponding to a region within amino acids 1 - 161 of Human ENTPD5 (NP_001240)

  • 阳性对照
    • 293T, A431, H1299, HeLa and HepG2 cell lysates

性能

应用

Our Abpromise guarantee covers the use of ab96067 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 48 kDa.

靶标

  • 功能Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
  • 组织特异性Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues.
  • 通路Protein modification; protein glycosylation.
  • 序列相似性Belongs to the GDA1/CD39 NTPase family.
  • 翻译后修饰N-glycosylated; high-mannose type.
  • 细胞定位Endoplasmic reticulum lumen.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD39 like 4 antibody
    • AI196558 antibody
    • AI987697 antibody
    • CD39 antigen like 4 antibody
    • CD39 antigen-like 4 antibody
    • CD39 like 4 antibody
    • CD39L4 antibody
    • Ectonucleoside triphosphate diphosphohydrolase 5 antibody
    • ENTP5_HUMAN antibody
    • Entpd5 antibody
    • ER UDPase antibody
    • ER-UDPase antibody
    • GDPase ENTPD5 antibody
    • Guanosine-diphosphatase ENTPD5 antibody
    • MGC163357 antibody
    • MGC163359 antibody
    • mNTPase antibody
    • NTPDase 5 antibody
    • Nucleoside diphosphatase antibody
    • PCPH antibody
    • Pcph proto oncogene protein antibody
    • Proto oncogene CPH antibody
    • UDPase ENTPD5 antibody
    • Uridine-diphosphatase ENTPD5 antibody
    see all

Anti-ENTPD5 antibody 图像

  • All lanes : Anti-ENTPD5 antibody (ab96067) at 1/1000 dilution

    Lane 1 : A431 whole cell lysate
    Lane 2 : H1299 whole cell lysate
    Lane 3 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 48 kDa

Anti-ENTPD5 antibody (ab96067)参考文献

ab96067 has not yet been referenced specifically in any publications.

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