概述

  • 产品名称Anti-ENTPD5抗体
    参阅全部 ENTPD5 一抗
  • 描述
    兔多克隆抗体to ENTPD5
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 85-134 (SVKPGLSAFV DQPKQGAETV QGLLEVAKDS IPRSHWKKTP VVLKATAGLR) of Human ENTPD5 (NP_001240).

  • 阳性对照
    • HT1080 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab118660 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
  • 组织特异性Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues.
  • 通路Protein modification; protein glycosylation.
  • 序列相似性Belongs to the GDA1/CD39 NTPase family.
  • 翻译后修饰N-glycosylated; high-mannose type.
  • 细胞定位Endoplasmic reticulum lumen.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD39 like 4 antibody
    • AI196558 antibody
    • AI987697 antibody
    • CD39 antigen like 4 antibody
    • CD39 antigen-like 4 antibody
    • CD39 like 4 antibody
    • CD39L4 antibody
    • Ectonucleoside triphosphate diphosphohydrolase 5 antibody
    • ENTP5_HUMAN antibody
    • Entpd5 antibody
    • ER UDPase antibody
    • ER-UDPase antibody
    • GDPase ENTPD5 antibody
    • Guanosine-diphosphatase ENTPD5 antibody
    • MGC163357 antibody
    • MGC163359 antibody
    • mNTPase antibody
    • NTPDase 5 antibody
    • Nucleoside diphosphatase antibody
    • PCPH antibody
    • Pcph proto oncogene protein antibody
    • Proto oncogene CPH antibody
    • UDPase ENTPD5 antibody
    • Uridine-diphosphatase ENTPD5 antibody
    see all

Anti-ENTPD5 antibody 图像

  • Anti-ENTPD5 antibody (ab118660) at 1 µg/ml + HT1080 cell lysate at 10 µg

    Predicted band size : 48 kDa

Anti-ENTPD5 antibody (ab118660)参考文献

ab118660 has not yet been referenced specifically in any publications.

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