功能In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP.
组织特异性Brain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes.
Western blot - ENTPD2 antibody [EPR3885] (ab110711)
All lanes : Anti-ENTPD2 antibody [EPR3885] (ab110711) at 1/1000 dilution
Lane 1 : Human placenta cell lysate Lane 2 : JAR cell lysate Lane 3 : Human fetal kidney cell lysate Lane 4 : U-87MG cell lysate
Lysates/proteins at 10 µg per lane.
Predicted band size : 54 kDa
Anti-ENTPD2 antibody [EPR3885] (ab110711)参考文献
This product has been referenced in:
Visovatti SH et al. Increased CD39 nucleotidase activity on microparticles from patients with idiopathic pulmonary arterial hypertension. PLoS One7:e40829 (2012).
Read more (PubMed: 22792409) »