Anti-Enterokinase抗体[MM0259- 8S12] (ab89458)

概述

  • 产品名称Anti-Enterokinase抗体[MM0259- 8S12]
    参阅全部 Enterokinase 一抗
  • 描述
    小鼠单克隆抗体[MM0259- 8S12] to Enterokinase
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant Human Enterokinase.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明IgG fraction of culture supernatant purified by Protein G affinity chromatography and 0.2 µm filtered.
  • 克隆单克隆
  • 克隆编号MM0259- 8S12
  • 同种型IgG2
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab89458 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 113 kDa.

靶标

  • 功能Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
  • 组织特异性Intestinal brush border.
  • 疾病相关Defects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD) [MIM:226200]; a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive.
  • 序列相似性Belongs to the peptidase S1 family.
    Contains 2 CUB domains.
    Contains 2 LDL-receptor class A domains.
    Contains 1 MAM domain.
    Contains 1 peptidase S1 domain.
    Contains 1 SEA domain.
    Contains 1 SRCR domain.
  • 翻译后修饰The chains are derived from a single precursor that is cleaved by a trypsin-like protease.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • PRSS 7 antibody
    • PRSS7 antibody
    • Enterokinase antibody
    • Enterokinase catalytic subunit antibody
    • Enteropeptidase antibody
    • Enteropeptidase catalytic light chain antibody
    • Enteropeptidase non catalytic heavy chain antibody
    • ENTK antibody
    • ENTK_HUMAN antibody
    • PROENTEROKINASE antibody
    • protease, serine, 7 (enterokinase) antibody
    • PRSS7 antibody
    • Serine protease 7 antibody
    • TMPRSS15 antibody
    • Transmembrane protease serine 15 antibody
    see all

Anti-Enterokinase antibody [MM0259- 8S12] (ab89458)参考文献

ab89458 has not yet been referenced specifically in any publications.

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