概述

  • 产品名称
  • 描述
    兔多克隆抗体to ENSA
  • 经测试应用
    适用于: WB, ICCmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 1-102 of Human ENSA (NP_004427).

  • 阳性对照
    • A549 whole cell lysate HeLa whole cell lysate HCT116 whole cell lysate HeLa cells (methanol fixed)

性能

应用

Our Abpromise guarantee covers the use of ab125873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 13 kDa.
ICC 1/100 - 1/500.

靶标

  • 相关性
    ENSA (Alpha endosulfine) is expressed in a wide range of tissues including muscle, brain, and endocrine tissues. The recombinant protein inhibits binding of labeled glibenclamide to beta cell membranes. It also inhibits cloned K(ATP) channel currents and thereby stimulates insulin secretion. It was proposed that endosulfine is an endogenous regulator of the K(ATP) channel, which has a key role in the control of insulin release and, more generally, couples cell metabolism to electrical activity.
  • 细胞定位
    Cytoplasmic
  • 数据库链接
  • 别名
    • Alpha endosulfine antibody
    • ARPP 19e antibody
    • Endosulfine alpha antibody

Anti-ENSA antibody 图像

  • Anti-ENSA antibody (ab125873) at 1/1000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size : 13 kDa
    15% SDS PAGE
  • Methanol-fixed HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for ENSA (green) using ab125873 at 1/500 dilution in ICC/IF. Blue: Hoechst 33343 staining.

Anti-ENSA antibody (ab125873)参考文献

ab125873 has not yet been referenced specifically in any publications.

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