概述

  • 产品名称
  • 描述
    兔多克隆抗体to ENPP7
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    antigen sequence: LEVEPFESVH VYELMCRLLG IVPEANDGHL ATLLPMLHTE SALPPDGRPT LLPKGRSALP PSSRPLLVMG LLGTVILLSE, corresponding to amino acids 377-456 of Human ENPP7 (UniProt ID: Q6UWV6).

  • 阳性对照
    • Human colon tissue

性能

应用

Our Abpromise guarantee covers the use of ab121827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    Converts sphingomyelin to ceramide. Also has phospholipase C activity toward palmitoyl lyso-phosphocholine. Does not appear to have nucleotide pyrophosphatase activity.
  • 组织特异性
    Detected in the colon (at protein level). Expressed in the duodenum, jejunum and liver and at low levels in the ileum. Expression was very low in the esophagus, stomach and colon.
  • 序列相似性
    Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
  • 翻译后修饰
    N-glycosylated; required for activity and transport to the plasma membrane.
  • 细胞定位
    Membrane. Localized at the surface of the microvillar membrane in small intestine enterocytes, and in endosome-like structures situated beneath the microvillar membrane, and in Golgi complex.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ALK SMase antibody
    • Alk-SMase antibody
    • Alkaline sphingomyelin phosphodiesterase antibody
    • E-NPP 7 antibody
    • Ectonucleotide pyrophosphatase/phosphodiesterase 7 antibody
    • Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 antibody
    • ENPP7 antibody
    • ENPP7_HUMAN antibody
    • Intestinal alkaline sphingomyelinase antibody
    • NPP-7 antibody
    see all

Anti-ENPP7 antibody 图像

  • ab121827, at a 1/40 dilution, staining ENPP7 in paraffin embedded Human colon tissue by Immunohistochemistry.

Anti-ENPP7 antibody (ab121827)参考文献

ab121827 has not yet been referenced specifically in any publications.

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