Anti-Endomorphin 1 & 2抗体(ab10290)

概述

  • 产品名称Anti-Endomorphin 1 & 2抗体
  • 描述
    兔多克隆抗体to Endomorphin 1 & 2
  • 特异性Sensitivity has been determined by ELISA. Less than 1ng of antibody could be detected after binding to Endomorphin 2 which is conjugated to titer plate: Endomorphin 2 = 100 Endomorphin 1 = 70 Leu5-Enkephalin = <0.01 Met5-Enkephalin = <0.03 beta-Endorphin = <0.01
  • 经测试应用适用于: IHC-Fr, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human, Pig, Monkey
  • 免疫原

    Synthetic peptide conjugated to BSA.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab10290 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use a concentration of 3 - 10 µg/ml.
ELISA Use at an assay dependent concentration.

靶标

  • 相关性Recently, endogenous agonists for the mu-opiate receptor, were first isolated from bovine brain [Nature,386, 499 (1997)]. These are endomorphin-1; Tyr-Pro-Trp-Phe-NH2, and endomorphin-2; Tyr-Pro-Phe-Phe-NH2. The isolation of relatively large amounts of endomorphin-1 and endomorphin-2 from human brain cortex has also reported [Peptides,18, 1635 (1997)]. The immunoreactivity for endomorphin was also detected in rat brain near the mu-opiate receptor containing neurons, but the molecular form of the rat peptide has not yet been elucidated [Peptides,18, 1641 (1997)]. These observations may be considered to indicate that endomorphin-1 and 2 are common mu-opiate agonists in mammals. In addition to the originally discovered mu-opiate agonistic function, these peptides have been reported to show hypotensive activity and Ca2+ channel current inhibitory activity [Biochem. Biophys. Res. Commun.,235, 567 (1997)]. Endomorphins would be useful for the study of pain perception together with some other biological functions in the body.

Anti-Endomorphin 1 & 2 antibody 图像

  • ab10290 staining Endomorphin 1 & 2 in rat paraventricular thalamic nucleus by Immunohistochemistry (PFA perfusion fixed frozen sections).

Anti-Endomorphin 1 & 2 antibody (ab10290)参考文献

ab10290 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Endomorphins are 4-amino-acid peptides with molecular weight ~ 480 Daltons. Peptides with such a small weight cannot be run by western blotting - there is no such a gel that would allow retain such small peptides. Secon...

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