Anti-ENC1抗体[EPR5406(B)] (ab124902)


  • 产品名称Anti-ENC1抗体[EPR5406(B)]
    参阅全部 ENC1 一抗
  • 描述
    兔单克隆抗体[EPR5406(B)] to ENC1
  • 经测试应用适用于: WB, IHC-P, ICC/IFmore details
    不适用于: IP
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

  • 阳性对照
    • Human fetal brain lysate; Human brain tissue
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.



Our Abpromise guarantee covers the use of ab124902 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 66 kDa (predicted molecular weight: 66 kDa).
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF 1/50 - 1/100.
  • 应用说明Is unsuitable for IP.
  • 靶标

    • 功能Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. May be down-regulated in neuroblastoma tumors. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
    • 组织特异性Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas.
    • 通路Protein modification; protein ubiquitination.
    • 序列相似性Contains 1 BTB (POZ) domain.
      Contains 6 Kelch repeats.
    • 发展阶段Dramatically up-regulated upon neuronal differentiation.
    • 翻译后修饰Ubiquitinated and probably targeted for proteasome-independent degradation.
    • 细胞定位Nucleus matrix. Cytoplasm > cytoskeleton.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CCL 28 antibody
      • CCL28 antibody
      • Ectoderm neural cortex protein 1 antibody
      • Ectoderm-neural cortex protein 1 antibody
      • Ectodermal neural cortex (with BTB like domain) antibody
      • ENC 1 antibody
      • ENC-1 antibody
      • ENC1 antibody
      • ENC1_HUMAN antibody
      • FLJ39259 antibody
      • Kelch like 35 antibody
      • Kelch like 37 antibody
      • Kelch-like protein 37 antibody
      • KLHL 35 antibody
      • KLHL35 antibody
      • KLHL37 antibody
      • NRPB antibody
      • Nuclear matrix protein NRP/B antibody
      • Nuclear restricted protein BTB domain like (brain) antibody
      • OTTHUMP00000128235 antibody
      • OTTHUMP00000222054 antibody
      • p53 induced gene 10 protein antibody
      • p53-induced gene 10 protein antibody
      • PIG 10 antibody
      • PIG10 antibody
      • TP53I10 antibody
      • Tumor protein p53 inducible protein 10 antibody
      see all

    Anti-ENC1 antibody [EPR5406(B)] 图像

    • Anti-ENC1 antibody [EPR5406(B)] (ab124902) at 1/1000 dilution + Human brain fetal lysate at 10 µg

      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 66 kDa
      Observed band size : 66 kDa
    • ab124902, at 1/100 dilution, staining ENC1 in paraffin-embedded Human brain tissue by Immunohistochemistry.
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-ENC1 antibody [EPR5406(B)] (ab124902)参考文献

    ab124902 has not yet been referenced specifically in any publications.

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