概述

  • 产品名称Anti-ENC1抗体
    参阅全部 ENC1 一抗
  • 描述
    兔多克隆抗体to ENC1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (SVSVHENRKS RASSGSINIY LFHKSSYADS VLTHLNLLRQ QRLFTDVLLH) of Human ENC1 (NP_003624).

  • 阳性对照
    • ACHN cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab94561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 66 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. May be down-regulated in neuroblastoma tumors. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  • 组织特异性Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Contains 1 BTB (POZ) domain.
    Contains 6 Kelch repeats.
  • 发展阶段Dramatically up-regulated upon neuronal differentiation.
  • 翻译后修饰Ubiquitinated and probably targeted for proteasome-independent degradation.
  • 细胞定位Nucleus matrix. Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CCL 28 antibody
    • CCL28 antibody
    • Ectoderm neural cortex protein 1 antibody
    • Ectoderm-neural cortex protein 1 antibody
    • Ectodermal neural cortex (with BTB like domain) antibody
    • ENC 1 antibody
    • ENC-1 antibody
    • ENC1 antibody
    • ENC1_HUMAN antibody
    • FLJ39259 antibody
    • Kelch like 35 antibody
    • Kelch like 37 antibody
    • Kelch-like protein 37 antibody
    • KLHL 35 antibody
    • KLHL35 antibody
    • KLHL37 antibody
    • NRPB antibody
    • Nuclear matrix protein NRP/B antibody
    • Nuclear restricted protein BTB domain like (brain) antibody
    • OTTHUMP00000128235 antibody
    • OTTHUMP00000222054 antibody
    • p53 induced gene 10 protein antibody
    • p53-induced gene 10 protein antibody
    • PIG 10 antibody
    • PIG10 antibody
    • TP53I10 antibody
    • Tumor protein p53 inducible protein 10 antibody
    see all

Anti-ENC1 antibody 图像

  • Anti-ENC1 antibody (ab94561) at 1 µg/ml (in 5% skim milk / PBS buffer) + ACHN cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 66 kDa

Anti-ENC1 antibody (ab94561)参考文献

ab94561 has not yet been referenced specifically in any publications.

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