概述

  • 产品名称Anti-ENAM抗体
  • 描述
    小鼠单克隆抗体to ENAM
  • 经测试应用适用于: WB, ELISA, Sandwich ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 1043-1142 of Human ENAM with proprietary tag (NP_114095).

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa

应用

Our Abpromise guarantee covers the use of ab118134 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 129 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

靶标

  • 功能Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation.
  • 组织特异性Expressed in tooth particularly in odontoblast, ameloblast and cementoblast.
  • 疾病相关Defects in ENAM are the cause of amelogenesis imperfecta hypoplastic type 1B (AI1B) [MIM:104500]. AI1B is an autosomal dominant defect of enamel formation. Clinical manifestations may be variable. Some cases present with generalized enamel hypoplasia resulting in small, smooth, yellow and spaced teeth (smooth hypoplastic AI). Others show horizontal rows of pits, grooves or a hypoplastic area in the enamel (local hypoplastic AI).
    Defects in ENAM are the cause of amelogenesis imperfecta type 1C (AI1C) [MIM:204650]; also known as amelogenesis imperfecta hypoplastic with or without openbite malocclusion. AI1C is an autosomal recessive defect of dental enamel formation. Teeth show hypoplastic and unmineralized enamel, and a yellow-brown discoloration. Enamel defects can be associated with facial and oral features including vertical dysgnathia and anterior openbite malocclusion.
  • 细胞定位Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ADAI antibody
    • AI1C antibody
    • AIH2 antibody
    • Amelogenesis imperfecta 2, hypocalcification (autosomal dominant) antibody
    • ENAM antibody
    • ENAM_HUMAN antibody
    • Enamelin antibody
    • OTTHUMP00000216417 antibody
    see all

Anti-ENAM antibody 图像

  • Anti-ENAM antibody (ab118134) at 5 µg/ml + recombinant immunogen at 0.2 µg

    Predicted band size : 129 kDa
  • Detection limit for recombinant tagged ENAM is 0.03 ng/ml as a capture antibody.

Anti-ENAM antibody (ab118134)参考文献

ab118134 has not yet been referenced specifically in any publications.

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