概述

  • 产品名称Anti-EMX2抗体
    参阅全部 EMX2 一抗
  • 描述
    兔多克隆抗体to EMX2
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Mouse, Human
  • 免疫原

    Three synthetic peptides derived from human EMX2, conjugated to KLH.

  • 阳性对照
    • An anti thio tested on an induced culture of E.coli.

性能

应用

Our Abpromise guarantee covers the use of ab86004 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明Direct ELISA: 1/19000.
    WB: 1/1000. Predicted molecular weight: 28 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
    • 组织特异性Cerebral cortex.
    • 疾病相关Defects in EMX2 are the cause of schizencephaly (SCHZC) [MIM:269160]. Schizencephaly is an extremely rare human congenital disorder characterized by a full-thickness cleft within the cerebral hemispheres. These clefts are lined with gray matter and most commonly involve the parasylvian regions. Large portions of the cerebral hemispheres may be absent and replaced by cerebro-spinal fluid.
    • 序列相似性Belongs to the EMX homeobox family.
      Contains 1 homeobox DNA-binding domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Empty spiracles homeobox 2 antibody
      • Empty spiracles homolog 2 (Drosophila) antibody
      • Empty spiracles homolog 2 antibody
      • Empty spiracles like protein 2 antibody
      • Empty spiracles-like protein 2 antibody
      • EMX 2 antibody
      • EMX2 antibody
      • EMX2_HUMAN antibody
      • Homeobox protein EMX 2 antibody
      • Homeobox protein EMX2 antibody
      see all

    Anti-EMX2 antibody 图像

    • Lane 1 : Anti-EMX2 antibody (ab86004) at 1/1000 dilution (in 5% non fat milk PBST solution incubated for 60 minutes)
      Lane 2 : Anti-EMX2 antibody (ab86004) (in 5% non fat milk PBST solution incubated for 60 minutes)

      Lane 1 : uninduced culture of E. coli (plus anti thio at 1/5000 dilution)
      Lane 2 : induced culture of E. coli (plus anti thio at 1/5000 dilution)

      Secondary
      anti-Rabbit IgG HRP conjugate incubated for 60 minutes at 1/1000 dilution

      Predicted band size : 28 kDa
      Observed band size : 42 kDa (why is the actual band size different from the predicted?)

    Anti-EMX2 antibody (ab86004)参考文献

    ab86004 has not yet been referenced specifically in any publications.

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