概述

  • 产品名称
  • 描述
    兔多克隆抗体to EMR3
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from the C-terminal of human EMR3.

  • 阳性对照
    • Extracts from Jurkat cells.

性能

应用

Our Abpromise guarantee covers the use of ab75283 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 73 kDa.
ELISA 1/10000.

靶标

  • 相关性
    EMR3 is a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing of this gene results in two transcript variants encoding two distinct isoforms. EMR3 has been reported to be expressed in neutrophils, monocytes, and macrophages. ESTs have been isolated from liver/spleen and mixed libraries.
  • 细胞定位
    Cell membrane; Multi-pass membrane protein. EMR3 subunit alpha: Secreted, extracellular space. Note: A soluble form is also detected.
  • 数据库链接
  • 别名
    • Egf like module containing mucin like hormone receptor like 3 antibody
    • Egf like module containing mucin like receptor 3 antibody
    • EGF like module containing mucin like receptor EMR3 antibody
    • EMR 3 antibody

图片

  • All lanes : Anti-EMR3 antibody (ab75283) at 1/500 dilution

    Lane 1 : Extracts from Jurkat cells
    Lane 2 : Extracts from Jurkat cells with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 73 kDa
    Observed band size : 73 kDa
    Additional bands at : 30 kDa,40 kDa,45 kDa. We are unsure as to the identity of these extra bands.

实验方案

文献

ab75283 has not yet been referenced specifically in any publications.

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