Anti-ELYS抗体[2318C1a] (ab53540)

概述

  • 产品名称Anti-ELYS抗体[2318C1a]
    参阅全部 ELYS 一抗
  • 描述
    小鼠单克隆抗体[2318C1a] to ELYS
  • 经测试应用适用于: Dot blot, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment

性能

应用

Our Abpromise guarantee covers the use of ab53540 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Dot blot Use at an assay dependent dilution.
WB Use at an assay dependent dilution. Predicted molecular weight: 253 kDa.

靶标

  • 功能Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.
  • 序列相似性Belongs to the ELYS family.
    Contains 1 A.T hook DNA-binding domain.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm. Nucleus matrix. Chromosome > centromere > kinetochore. Nucleus > nucleoplasm. Nucleus > nuclear pore complex. Localizes to the nuclear pore complex (NPC) throughout interphase. Localizes to the kinetochore from prophase, and this appears to require the Nup107-160 subcomplex of the NPC. Localizes to the periphery of chromatin from late anaphase.
  • Information by UniProt
  • 数据库链接
  • 形式There are 2 isoforms produced by alternative splicing.
  • 别名
    • ahctf1 antibody
    • AT hook containing transcription factor 1 antibody
    • DKFZp434N093 antibody
    • ELYS antibody
    • ELYS transcription factor like protein TMBS62 antibody
    • ELYS_HUMAN antibody
    • Embryonic large molecule derived from yolk sac antibody
    • MST108 antibody
    • MSTP108 antibody
    • Protein ELYS antibody
    • Protein MEL-28 antibody
    • Putative AT-hook-containing transcription factor 1 antibody
    • TMBS62 antibody
    see all

Anti-ELYS antibody [2318C1a] 图像

Anti-ELYS antibody [2318C1a] (ab53540)参考文献

ab53540 has not yet been referenced specifically in any publications.

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