概述

性能

应用

Our Abpromise guarantee covers the use of ab2271 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 75 kDa (predicted molecular weight: 81 kDa).

靶标

  • 功能
    Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • 序列相似性
    Contains 1 ELMO domain.
    Contains 1 PH domain.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CED 12 antibody
    • Ced 12 homolog 3 antibody
    • CED12 antibody
    • ELMO 3 antibody
    • ELMO3 antibody
    • ELMO3_HUMAN antibody
    • Engulfment and cell motility 3 antibody
    • Engulfment and cell motility protein 3 antibody
    • FLJ13824 antibody
    see all

图片

实验方案

文献

This product has been referenced in:
  • Ikhapoh IA  et al. Atherogenic Cytokines Regulate VEGF-A-Induced Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells into Endothelial Cells. Stem Cells Int 2015:498328 (2015). IF . Read more (PubMed: 26106428) »

See 1 Publication for this product

客户评价及客户问答

Thank you for your reply.

I have now arranged for the anti-ANKH antibody (ab129001) to be sent to you free of charge as discussed.

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If I can be of any further assistance, please do not ...

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Thank you for contacting Abcam regarding our ELMO3 antibodies ab76402 and ab2271. I have reviewed the datasheets for both of these products and the information regarding the molecular weights of these proteins. According to SwissProt, there are three i...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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