概述

  • 产品名称Anti-ELMO2抗体
    参阅全部 ELMO2 一抗
  • 描述
    山羊多克隆抗体to ELMO2
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Cow
  • 免疫原

    Synthetic peptide:C-

    PKEPSSYDFVYHYG

    (with a Cysteine residue linker), corresponding to C terminal amino acids 707-720 of Human ELMO2

  • 阳性对照
    • Human brain lysate Human prostate tissue

性能

应用

Our Abpromise guarantee covers the use of ab113976 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 83 kDa.
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
  • 组织特异性Widely expressed, with a higher expression in skeletal muscle, kidney and placenta.
  • 序列相似性Contains 1 ELMO domain.
    Contains 1 PH domain.
  • 细胞定位Cytoplasm. Cytoplasm > cytosol. Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CED 12 antibody
    • Ced 12 homolog 2 antibody
    • CED 12 homolog A antibody
    • CED 12A antibody
    • CED-12 antibody
    • ced-12 homolog 2 antibody
    • CED12 antibody
    • CED12 homolog A antibody
    • CED12, C. elegans, homolog of, 2 antibody
    • CED12A antibody
    • ELMO 2 antibody
    • ELMO-2 antibody
    • ELMO2 antibody
    • ELMO2_HUMAN antibody
    • Engulfment and cell motility 2 (ced 12 homolog, C. elegans) antibody
    • Engulfment and cell motility 2 antibody
    • Engulfment and cell motility gene 2 antibody
    • Engulfment and cell motility protein 2 antibody
    • FLJ11656 antibody
    • hCED 12A antibody
    • hCED-12A antibody
    • hCED12A antibody
    • KIAA1834 antibody
    • OTTHUMP00000031762 antibody
    • PH domain protein CED12A antibody
    • Protein ced 12 homolog A antibody
    • Protein ced-12 homolog A antibody
    see all

Anti-ELMO2 antibody 图像

  • Anti-ELMO2 antibody (ab113976) at 2 µg/ml + Human brain lysate in RIPA buffer at 30 µg

    Predicted band size : 83 kDa
  • ab113976, at 3.75 µg/ml, staining ELMO2 in formalin fixed paraffin embedded Human prostate by Immunohistochemistry.

Anti-ELMO2 antibody (ab113976)参考文献

ab113976 has not yet been referenced specifically in any publications.

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