概述

  • 产品名称Ellagic acid
  • 描述
    Selective, casein kinase 2 (CK2) inhibitor
  • 生物学描述Selective, ATP-competitive casein kinase 2 (CK2) inhibitor (Ki = 20 nM). Exhibits a multitude of biological activities including antioxidant, antiproliferative and pro-apoptotic activity.
  • 纯度> 99%

性能

  • 化学名称2,3,7,8-Tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
  • 分子量302.20
  • 化学结构Chemical Structure
  • 分子式C14H6O8
  • CAS编号476-66-4
  • 存放说明Store at -20°C. Store at -20°C long term. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under Desiccating conditions.
  • 溶解度概述Soluble in DMSO to 1 mM and in ethanol to 1 mM
  • 处理

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • 来源

    Tree bark

  • 研究领域

    Ellagic acid (ab120622)参考文献

    This product has been referenced in:
    • Cozza G  et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem 49:2363-6 (2006). Read more (PubMed: 16610779) »
    • Seeram NP  et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 16:360-7 (2005). Read more (PubMed: 15936648) »
    • Han DH  et al. Antioxidant and apoptosis-inducing activities of ellagic acid. Anticancer Res 26:3601-6 (0). Read more (PubMed: 17094489) »

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