Anti-Elafin/ESI抗体[TRAB2F] (ab81681)
Key features and details
- Mouse monoclonal [TRAB2F] to Elafin/ESI
- Suitable for: ELISA, IHC-P, WB
- Reacts with: Human
- Isotype: IgG2b
概述
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产品名称
Anti-Elafin/ESI抗体[TRAB2F]
参阅全部 Elafin/ESI 一抗 -
描述
小鼠单克隆抗体[TRAB2F] to Elafin/ESI -
宿主
Mouse -
经测试应用
适用于: ELISA, IHC-P, WBmore details
不适用于: IHC-Fr -
种属反应性
与反应: Human -
免疫原
Synthetic peptide corresponding to Elafin/ESI (C terminal) conjugated to keyhole limpet haemocyanin.
Sequence:AQEPVKGPVSTKPGSC
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.02% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
TRAB2F -
同种型
IgG2b -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab81681于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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ELISA |
Use at an assay dependent concentration.
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IHC-P |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 12 kDa.
Use under reducing conditions. |
说明 |
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ELISA
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 12 kDa. Use under reducing conditions. |
靶标
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功能
Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis. -
序列相似性
Contains 1 WAP domain. -
结构域
Consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize elafin covalently to specific sites on extracellular matrix proteins. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 5266 Human
- Omim: 182257 Human
- SwissProt: P19957 Human
- Unigene: 112341 Human
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别名
- Cementoin antibody
- ELAF_HUMAN antibody
- Elafin antibody
see all
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab81681 被引用在 3 文献中.
- Zakizadeh F et al. Upregulation of elafin expression in the fallopian tube of ectopic tubal pregnancies compared to the normal tubes. J Reprod Immunol 141:103136 (2020). PubMed: 32485443
- Curciarello R et al. Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies. J Inflamm Res 13:233-243 (2020). PubMed: 32547155
- Desmet E et al. Towards the development of a RNAi-based topical treatment for psoriasis: Proof-of-concept in a 3D psoriasis skin model. Exp Dermatol 27:463-469 (2018). PubMed: 28833576