概述

  • 产品名称Anti-EIF5AL1抗体
  • 描述
    兔多克隆抗体to EIF5AL1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 101-130 of Human EIF5AL1 (NP_001093162.1)

  • 阳性对照
    • Ramos cell line lysates

性能

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应用

Our Abpromise guarantee covers the use of ab110502 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 17 kDa.

靶标

  • 功能mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
  • 序列相似性Belongs to the eIF-5A family.
  • 翻译后修饰eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).
  • 细胞定位Cytoplasm. Nucleus. Endoplasmic reticulum membrane. Nucleus > nuclear pore complex. Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions.
  • Information by UniProt
  • 数据库链接
  • 别名
    • bA342M3.3 antibody
    • eIF-5A-1-like antibody
    • eIF-5A1-like antibody
    • EIF5AL1 antibody
    • EIF5AP1 antibody
    • Eukaryotic initiation factor 5A isoform 1-like antibody
    • Eukaryotic translation initiation factor 5A-1-like antibody
    • IF5AL_HUMAN antibody
    • RP11-342M3.3 antibody
    see all

Anti-EIF5AL1 antibody 图像

  • Anti-EIF5AL1 antibody (ab110502) at 1/100 dilution + Ramos cell line lysates at 35 µg

    Predicted band size : 17 kDa

Anti-EIF5AL1 antibody (ab110502)参考文献

ab110502 has not yet been referenced specifically in any publications.

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