概述

  • 产品名称Anti-eIF3s8抗体
    参阅全部 eIF3s8 一抗
  • 描述
    兔多克隆抗体to eIF3s8
  • 经测试应用适用于: WB, IPmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Rabbit, Horse, Guinea pig, Cow, Dog, Chimpanzee, Gorilla, Chinese Hamster, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to Human eIF3s8 aa 850-913 (C terminal).

  • 阳性对照
    • Whole cell lysate from HEK293 (human), C2C12 (mouse), and L6 (Rat) cells.

性能

应用

Our Abpromise guarantee covers the use of ab19360 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/15000 - 1/30000. Detects a band of approximately 98 kDa (predicted molecular weight: 105 kDa).
IP Use at 2-10 µg/mg of lysate.

靶标

  • 功能Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
  • 序列相似性Belongs to the eIF-3 subunit C family.
    Contains 1 PCI domain.
  • 翻译后修饰Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cell migration inducing protein 17 antibody
    • eIF 3c antibody
    • eIF3 p110 antibody
    • eIF3-p110 antibody
    • eIF3c antibody
    • EIF3C_HUMAN antibody
    • EIF3CL antibody
    • EIF3S8 antibody
    • EIF3S8 protein antibody
    • Eukaryotic translation initiation factor 3 subunit 8 (110kD) antibody
    • Eukaryotic translation initiation factor 3 subunit 8 110kDa antibody
    • Eukaryotic translation initiation factor 3 subunit 8 antibody
    • Eukaryotic translation initiation factor 3 subunit C antibody
    see all

Anti-eIF3s8 antibody 图像



  • Predicted band size : 105 kDa


    ab19360 at 0.04µg/ml for Western Blot (A and B) and at 5µg/mg for immunoprecipitation (B), staining (5, 15 or 50µg for Western blot) human HEK293, mouse C2C12 and rat L6 cells (A) and (1mg for immunoprecipitation) whole cell lysate from HEK293 cells (B). Detection was by chemiluminescence with exposure times of two to four minutes.

Anti-eIF3s8 antibody (ab19360)参考文献

ab19360 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab19360.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"