概述

  • 产品名称Anti-EIF3S4抗体
    参阅全部 EIF3S4 一抗
  • 描述
    鸡多克隆抗体to EIF3S4
  • 特异性Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. This subunit binds to the 18S rRNA.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide, corresponding to N terminal amino acids 1/245 of Human EIF3S4

  • 常规说明


    eIF-3 is composed of at least 12 different subunits. Interacts with EIF3S12. Contains 1 RRM (RNA recognition motif) domain. Pathways: Reactome Event:Gene Expression 74160 Reactome Event:Translation 72766

性能

应用

Our Abpromise guarantee covers the use of ab37685 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Predicted molecular weight: 35 kDa.

靶标

  • 功能Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
  • 序列相似性Belongs to the eIF-3 subunit G family.
    Contains 1 RRM (RNA recognition motif) domain.
  • 翻译后修饰Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
  • 细胞定位Cytoplasm. Nucleus. Cytoplasm > perinuclear region. Colocalizes with AIFM1 in the nucleus and perinuclear region.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 44kDa antibody
    • Anti EIF3S4 antibody
    • eIF 3 delta antibody
    • eIF 3 RNA binding subunit antibody
    • eIF-3 RNA-binding subunit antibody
    • eIF-3-delta antibody
    • eIF3 delta antibody
    • eIF3 p42 antibody
    • eIF3 p44 antibody
    • eIF3g antibody
    • EIF3G_HUMAN antibody
    • EIF3S4 antibody
    • EIF3S4 antibody antibody
    • EIF3S4, formerly antibody
    • Eukaryotic translation initiation factor 3 antibody
    • Eukaryotic translation initiation factor 3 RNA binding subunit antibody
    • Eukaryotic translation initiation factor 3 RNA-binding subunit antibody
    • Eukaryotic translation initiation factor 3 subunit 4 antibody
    • Eukaryotic translation initiation factor 3 subunit 4 delta 44 kD antibody
    • Eukaryotic translation initiation factor 3 subunit G antibody
    • Eukaryotic translation initiation factor 3 subunit p42 antibody
    • Eukaryotic translation initiation factor 3, subunit 4, formerly antibody
    • Subunit 4 (delta 44kD) antibody
    • Subunit 4 delta antibody
    see all

Anti-EIF3S4 antibody 图像



  • Predicted band size : 35 kDa

Anti-EIF3S4 antibody (ab37685)参考文献

ab37685 has not yet been referenced specifically in any publications.

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