概述

  • 产品名称Anti-EIF3S3抗体
    参阅全部 EIF3S3 一抗
  • 描述
    小鼠单克隆抗体to EIF3S3
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow
  • 免疫原

    Recombinant fragment with tag: YDPIKTAQGS LSLKAYRLTP KLMEVCKEKD FSPEALKKAN ITFEYMFEEV PIVIKNSHLI NVLMWELEKK SAVADKHELL SLASSNHLGK NLQLLMDRV, corresponding to amino acids 152-251 of Human EIF3S3

  • 阳性对照
    • Jurkat whole cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab60942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Detects a band of approximately 37 kDa (predicted molecular weight: 40 kDa).
ELISA Use at an assay dependent dilution.

靶标

  • 功能Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
  • 序列相似性Belongs to the eIF-3 subunit H family.
    Contains 1 MPN (JAB/Mov34) domain.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • eIF-3-gamma antibody
    • eIF3 gamma antibody
    • eIF3 p40 antibody
    • eIF3 p40 subunit antibody
    • eIF3h antibody
    • EIF3H_HUMAN antibody
    • EIF3S3 antibody
    • Eukaryotic translation initiation factor 3 subunit 3 antibody
    • Eukaryotic translation initiation factor 3 subunit H antibody
    • MGC102958 antibody
    see all

Anti-EIF3S3 antibody 图像

  • Anti-EIF3S3 antibody (ab60942) + Jurkat whole cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
    Developed using the ECL technique

    Predicted band size : 40 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)

Anti-EIF3S3 antibody (ab60942)参考文献

ab60942 has not yet been referenced specifically in any publications.

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