概述

  • 产品名称Anti-eIF3K抗体
    参阅全部 eIF3K 一抗
  • 描述
    兔多克隆抗体to eIF3K
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to an internal region of Human eIF3K.

  • 阳性对照
    • HeLa cell lysate

性能

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应用

Our Abpromise guarantee covers the use of ab92740 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: 1/40000.
    WB: 1/500 - 1/1000. Predicted molecular weight: 25 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
    • 组织特异性Ubiquitous, with the highest levels of expression in brain, testis and kidney.
    • 序列相似性Belongs to the eIF-3 subunit K family.
    • 细胞定位Nucleus. Cytoplasm.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ARG134 antibody
      • eIF 3 p25 antibody
      • eIF 3 p28 antibody
      • eIF-3 p25 antibody
      • eIF-3 p28 antibody
      • EIF3-p28 antibody
      • eif3k antibody
      • EIF3K_HUMAN antibody
      • EIF3S12 antibody
      • Eukaryotic translation initiation factor 3 subunit 12 antibody
      • Eukaryotic translation initiation factor 3 subunit K antibody
      • HSPC029 antibody
      • M9 antibody
      • MSTP001 antibody
      • Muscle specific gene M9 protein antibody
      • Muscle-specific gene M9 protein antibody
      • PLAC 24 antibody
      • PLAC-24 antibody
      • PLAC24 antibody
      • PRO1474 antibody
      • PTD001 antibody
      see all

    Anti-eIF3K antibody 图像

    • All lanes : Anti-eIF3K antibody (ab92740) at 1/500 dilution

      Lane 1 : HeLa cell extract
      Lane 2 : HeLa cell extract with blocking peptide at 10 µg

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 25 kDa

    Anti-eIF3K antibody (ab92740)参考文献

    ab92740 has not yet been referenced specifically in any publications.

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