概述

  • 产品名称Anti-eIF3K抗体
    参阅全部 eIF3K 一抗
  • 描述
    鸡多克隆抗体to eIF3K
  • 特异性ab26937 recognises eukaryotic translation initiation factor 3 subunit 12(eIF3k, HSP27).
  • 经测试应用适用于: IHC-P, WBmore details
  • 种属反应性
    与反应: Human, Chimpanzee
    预测可用于: Mouse, Cow, Xenopus laevis, Zebrafish
  • 免疫原

    Fusion protein: LYQFNPAFFQ TTVTAQILLK ALTNLPHTDF TLCKCMIDQA HQ, corresponding to amino acids 53/94 of Human eIF3K

  • 阳性对照
    • Oral cancer epithelium

性能

应用

Our Abpromise guarantee covers the use of ab26937 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/500.
WB 1/3000. Predicted molecular weight: 25 kDa.

靶标

  • 功能Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
  • 组织特异性Ubiquitous, with the highest levels of expression in brain, testis and kidney.
  • 序列相似性Belongs to the eIF-3 subunit K family.
  • 细胞定位Nucleus. Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ARG134 antibody
    • eIF 3 p25 antibody
    • eIF 3 p28 antibody
    • eIF-3 p25 antibody
    • eIF-3 p28 antibody
    • EIF3-p28 antibody
    • eif3k antibody
    • EIF3K_HUMAN antibody
    • EIF3S12 antibody
    • Eukaryotic translation initiation factor 3 subunit 12 antibody
    • Eukaryotic translation initiation factor 3 subunit K antibody
    • HSPC029 antibody
    • M9 antibody
    • MSTP001 antibody
    • Muscle specific gene M9 protein antibody
    • Muscle-specific gene M9 protein antibody
    • PLAC 24 antibody
    • PLAC-24 antibody
    • PLAC24 antibody
    • PRO1474 antibody
    • PTD001 antibody
    see all

Anti-eIF3K antibody 图像

  • Immunohistochemical analysis of eIF3K expression in (A) oral cancer epithelium using 1/500 ab26937. (B) represents staining of oral epithelium, as negative control.

Anti-eIF3K antibody (ab26937)参考文献

ab26937 has not yet been referenced specifically in any publications.

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