Anti-eIF2B3抗体- Carboxyterminal end (ab71248)


  • 产品名称Anti-eIF2B3抗体- Carboxyterminal end
    参阅全部 eIF2B3 一抗
  • 描述
    兔多克隆抗体to eIF2B3 - Carboxyterminal end
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human eIF2B3 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • 阳性对照
    • A375 cell line lysate.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Ammonium Sulphate Precipitation
  • 纯化说明This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域


Our Abpromise guarantee covers the use of ab71248 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Detects a band of approximately 27 kDa (predicted molecular weight: 32 kDa).
ELISA 1/1000.


  • 功能Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
  • 疾病相关Defects in EIF2B3 are a cause of leukodystrophy with vanishing white matter (VWM) [MIM:603896]. VWM is a leukodystrophy that occurs mainly in children. Neurological signs include progressive cerebellar ataxia, spasticity, inconstant optic atrophy and relatively preserved mental abilities. The disease is chronic-progressive with, in most individuals, additional episodes of rapid deterioration following febrile infections or minor head trauma. While childhood onset is the most common form of the disorder, some severe forms are apparent at birth. A severe, early-onset form seen among the Cree and Chippewayan populations of Quebec and Manitoba is called Cree leukoencephalopathy. Milder forms may not become evident until adolescence or adulthood. Some females with milder forms of the disease who survive to adolescence exhibit ovarian dysfunction. This variant of the disorder is called ovarioleukodystrophy.
  • 序列相似性Belongs to the eIF-2B gamma/epsilon subunits family.
  • Information by UniProt
  • 数据库链接
  • 形式It localizes to the cytosol.
  • 别名
    • EI2BG_HUMAN antibody
    • EIF 2B antibody
    • eIF 2B GDP GTP exchange factor subunit gamma antibody
    • eIF-2B GDP-GTP exchange factor subunit gamma antibody
    • eIF2B-gamma antibody
    • Eif2b3 antibody
    • EIF2Bgamma antibody
    • Eukaryotic translation initiation factor 2B subunit 3 gamma antibody
    • Eukaryotic translation initiation factor 2B, gamma antibody
    • eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa antibody
    • OTTHUMP00000010262 antibody
    • OTTHUMP00000010263 antibody
    • Translation initiation factor eIF-2B subunit gamma antibody
    see all

Anti-eIF2B3 antibody - Carboxyterminal end 图像

  • Anti-eIF2B3 antibody - Carboxyterminal end (ab71248) at 1/100 dilution + A375 cell line lysate at 12.5 µg

    Predicted band size : 32 kDa
    Observed band size : 27 kDa (why is the actual band size different from the predicted?)

Anti-eIF2B3 antibody - Carboxyterminal end (ab71248)参考文献

ab71248 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab71248.
Please use the links above to contact us or submit feedback about this product.