Anti-eIF2A抗体(ab102786)

概述

  • 产品名称Anti-eIF2A抗体
    参阅全部 eIF2A 一抗
  • 描述
    兔多克隆抗体to eIF2A
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 444-473 (UniProt ID: Q9BY44) of Human eIF2A conjugated to KLH.

  • 阳性对照
    • Ramos cell line lysates; Human brain tissue

性能

应用

Our Abpromise guarantee covers the use of ab102786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 65 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.
  • 组织特异性Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta.
  • 序列相似性Belongs to the WD repeat EIF2A family.
    Contains 3 WD repeats.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 65 kDa eukaryotic translation initiation factor 2A antibody
    • CDA 02 antibody
    • CDA02 antibody
    • EIF 2 antibody
    • EIF 2A antibody
    • eIF-2A antibody
    • EIF2 antibody
    • eif2a antibody
    • EIF2A_HUMAN antibody
    • Eukaryotic translation initiation factor 2A 65kDa antibody
    • Eukaryotic translation initiation factor 2A antibody
    • MST089 antibody
    • MSTP004 antibody
    • MSTP089 antibody
    see all

Anti-eIF2A antibody 图像

  • Anti-eIF2A antibody (ab102786) at 1/100 dilution + Ramos cell line lysates at 35 µg

    Predicted band size : 65 kDa
  • ab102786, at a 1/50 dilution, staining eIF2 in formalin fixed, paraffin embedded Human brain tissue by Immunohistochemistry, followed by peroxidase conjugated secondary antibody and DAB staining.

Anti-eIF2A antibody (ab102786)参考文献

ab102786 has not yet been referenced specifically in any publications.

Product Wall

Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products.

I am sorry for the inconvenience this has caused. As requested, I have issued a free of charge ...

Read More

Thank you for contacting Abcam and thank you for bringing these issue to us. It does appear that these products should be listed as against eIF2A instead of eIF2 subunit alpha. I will make sure that this is brought to the attention of the appropria...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"