概述

  • 产品名称Anti-EHHADH抗体
    参阅全部 EHHADH 一抗
  • 描述
    兔多克隆抗体to EHHADH
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the C terminal region of Human EHHADH (NP_001957.2).

  • 阳性对照
    • WB: mouse liver and kidney tissue lysates IHC-P: human hepatocarcinoma

性能

应用

Our Abpromise guarantee covers the use of ab93172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 79 kDa.
IHC-P 1/50 - 1/100.

靶标

  • 组织特异性Liver and kidney. Lower amounts seen in the brain.
  • 通路Lipid metabolism; fatty acid beta-oxidation.
  • 序列相似性In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
    In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  • 翻译后修饰Acetylated, leading to enhanced enzyme activity. Acetylation is enhanced by up to 80% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with highest increase on Lys-346. Acetylation and enzyme activity increased by about 1.5% on addition of fatty acids.
  • 细胞定位Peroxisome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 3 hydroxyacyl CoA dehydrogenase antibody
    • 3,2 trans enoyl CoA isomerase antibody
    • 3-hydroxyacyl-CoA dehydrogenase antibody
    • ECHD antibody
    • ECHP_HUMAN antibody
    • EHHADH antibody
    • Enoyl Coenzyme A, hydratase/3 hydroxyacyl Coenzyme A dehydrogenase antibody
    • L 3 hydroxyacyl CoA dehydrogenase antibody
    • L bifunctional protein, peroxisomal antibody
    • L PBE antibody
    • LBFP antibody
    • LBP antibody
    • MGC120586 antibody
    • MS730 antibody
    • PBE antibody
    • PBFE antibody
    • Peroxisomal bifunctional enzyme antibody
    • Peroxisomal enoyl CoA hydratase antibody
    see all

Anti-EHHADH antibody 图像

  • All lanes : Anti-EHHADH antibody (ab93172) at 1/100 dilution

    Lane 1 : mouse liver tissue lysates
    Lane 2 : mouse kidney tissue lysates

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 79 kDa
  • ab93172, at a 1/50 dilution, staining EHHADH in formalin-fixed and paraffin-embedded Human hepatocarcinoma peroxidase-conjugated to a secondary antibody, followed by DAB staining.

Anti-EHHADH antibody (ab93172)参考文献

This product has been referenced in:
  • Tsoli M  et al. Depletion of white adipose tissue in cancer cachexia syndrome is associated with inflammatory signaling and disrupted circadian regulation. PLoS One 9:e92966 (2014). WB ; Mouse . Read more (PubMed: 24667661) »

See 1 Publication for this product

Product Wall

Thank you for your inquiry and I am sorry to hear that you are having some trouble with this antibody.

We sell the mouse liver whole cell lysate as ab29301:

http://www.abcam.com/Liver-Mouse-Whole-Cell-Lysate-normal-tissue-ab29301.ht...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"