概述

  • 产品名称Anti-EHD2抗体
    参阅全部 EHD2 一抗
  • 描述
    小鼠单克隆抗体to EHD2
  • 经测试应用适用于: WB, Sandwich ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment corresponding to amino acids 365-428 of Human EHD2 with proprietary 26 kDa tag (NP_055416).

  • 阳性对照
    • EHD2 transfected HeLa cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab118356 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 61 kDa.
Sandwich ELISA Use a concentration of 10 µg/ml.

靶标

  • 功能Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP.
  • 组织特异性Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle.
  • 序列相似性Contains 1 EF-hand domain.
    Contains 1 EH domain.
  • 结构域The EH domain interacts with Asn-Pro-Phe (NPF) motifs of target proteins.
  • 细胞定位Cell membrane. Endosome membrane. Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EH domain containing 2 antibody
    • EH domain containing 3 antibody
    • EH domain containing protein 2 antibody
    • EH domain-containing protein 2 antibody
    • EHD 2 antibody
    • Ehd2 antibody
    • EHD2_HUMAN antibody
    • EHD3 antibody
    • FLJ96617 antibody
    • PAST 2 antibody
    • PAST homolog 2 antibody
    • PAST2 antibody
    see all

Anti-EHD2 antibody 图像

  • Anti-EHD2 antibody (ab118356) at 5 µg/ml + Immunizing peptide at 0.2 µg

    Predicted band size : 61 kDa
  • Anti-EHD2 antibody (ab118356) at 5 µg/ml + EHD2 transfected HeLa cell lysate at 25 µg

    Predicted band size : 61 kDa
  • Detection limit for recombinant tagged EHD2 is 0.1 ng/ml as a capture antibody.

Anti-EHD2 antibody (ab118356)参考文献

ab118356 has not yet been referenced specifically in any publications.

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