概述

  • 产品名称Anti-EGR4抗体
    参阅全部 EGR4 一抗
  • 描述
    山羊多克隆抗体to EGR4
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee
  • 免疫原

    Synthetic peptide:

    NCGSQGDYQAAPE

    , corresponding to internal sequence amino acids 218-230 of human EGR4 (NP_001956.2)

  • 阳性对照
    • Human brain (hippocampus, cerebellum and frontal cortex) lysates

性能

应用

Our Abpromise guarantee covers the use of ab77342 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/4000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 51 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性EGR4(Early Growth Response protein 4) is a zinc-finger transcription factor that activates the transcription of genes whose products are required for mitogenesis and differentiation. EGR4 is closely related to nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR4 functionally cooperate with NFAT proteins and induce expression of IL2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
    • 细胞定位Nuclear
    • 数据库链接
    • 别名
      • AT133 antibody
      • Early growth response protein 4 antibody
      • Nerve growth factor induced clone C antibody
      • NGFI C antibody
      • NGFIC antibody
      • PAT133 antibody
      see all

    Anti-EGR4 antibody 图像

    • Anti-EGR4 antibody (ab77342) at 0.3 µg/ml + Human Brain (Hippocampus) lysate in RIPA buffer at 35 µg

      Predicted band size : 51 kDa
      Observed band size : 51 kDa

    Anti-EGR4 antibody (ab77342)参考文献

    ab77342 has not yet been referenced specifically in any publications.

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