Anti-EGR4抗体(ab77342)

概述

• 产品名称Anti-EGR4抗体
  参阅全部 EGR4 一抗
• 描述
  山羊多克隆抗体to EGR4
• 经测试应用适用于: WB, ELISAmore details
• 种属反应性
  与反应: Human
  预测可用于: Chimpanzee
• 免疫原

  Synthetic peptide:

  NCGSQGDYQAAPE

  , corresponding to internal sequence amino acids 218-230 of human EGR4 (NP_001956.2)
  Run BLAST with Run BLAST with
• 阳性对照
  • Human brain (hippocampus, cerebellum and frontal cortex) lysates

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• 存储溶液Preservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
• Concentration information loading...
• 纯度Immunogen affinity purified
• 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• 克隆多克隆
• 同种型IgG
• 研究领域
  • Epigenetics and Nuclear Signaling
  • Transcription
  • Domain Families
  • Zinc Finger

  • Epigenetics and Nuclear Signaling
  • Transcription
  • Transcription Factors

相关产品

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

应用

靶标

• 相关性EGR4(Early Growth Response protein 4) is a zinc-finger transcription factor that activates the transcription of genes whose products are required for mitogenesis and differentiation. EGR4 is closely related to nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR4 functionally cooperate with NFAT proteins and induce expression of IL2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
• 细胞定位Nuclear
• 数据库链接
  • Entrez Gene: 1961 Human
  • Omim: 128992 Human
  • SwissProt: Q05215 Human
  • Unigene: 3052 Human
• 别名
  • AT133 antibody
  • Early growth response protein 4 antibody
  • Nerve growth factor induced clone C antibody

  • NGFI C antibody
  • NGFIC antibody
  • PAT133 antibody

  see all