概述
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产品名称Anti-EGR4抗体
参阅全部 EGR4 一抗 -
描述山羊多克隆抗体to EGR4
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经测试应用适用于: WB, ELISAmore details
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种属反应性与反应: Human
预测可用于: Chimpanzee
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免疫原
Synthetic peptide:
NCGSQGDYQAAPE
, corresponding to internal sequence amino acids 218-230 of human EGR4 (NP_001956.2) -
阳性对照
- Human brain (hippocampus, cerebellum and frontal cortex) lysates
性能
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形式Liquid
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存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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存储溶液Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 -
Concentration information loading... -
纯度Immunogen affinity purified
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纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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克隆多克隆
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同种型IgG
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研究领域
相关产品
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Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab77342 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| WB | ||
| ELISA |
应用说明
Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/4000.
WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 51 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 51 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
靶标
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相关性EGR4(Early Growth Response protein 4) is a zinc-finger transcription factor that activates the transcription of genes whose products are required for mitogenesis and differentiation. EGR4 is closely related to nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR4 functionally cooperate with NFAT proteins and induce expression of IL2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
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细胞定位Nuclear
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数据库链接
- Entrez Gene: 1961 Human
- Omim: 128992 Human
- SwissProt: Q05215 Human
- Unigene: 3052 Human
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别名
- AT133 antibody
- Early growth response protein 4 antibody
- Nerve growth factor induced clone C antibody
see all
Anti-EGR4 antibody 图像
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Western blot - EGR4 antibody (ab77342)Anti-EGR4 antibody (ab77342) at 0.3 µg/ml + Human Brain (Hippocampus) lysate in RIPA buffer at 35 µg
Predicted band size : 51 kDa
Observed band size : 51 kDa
Anti-EGR4 antibody (ab77342)参考文献
ab77342 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"