概述

  • 产品名称Anti-EGR4抗体
    参阅全部 EGR4 一抗
  • 描述
    兔多克隆抗体to EGR4
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog, Drosophila melanogaster, Zebrafish
  • 免疫原

    Synthetic peptide (Human)

  • 阳性对照
    • Jurkat cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab50636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.

Peptide ELISA titre: 1/312500.

WB Use a concentration of 0.0625 µg/ml. Detects a band of approximately 46 kDa (predicted molecular weight: 51 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性EGR4(Early Growth Response protein 4) is a zinc-finger transcription factor that activates the transcription of genes whose products are required for mitogenesis and differentiation. EGR4 is closely related to nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR4 functionally cooperate with NFAT proteins and induce expression of IL2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • AT133 antibody
    • Early growth response protein 4 antibody
    • Nerve growth factor induced clone C antibody
    • NGFI C antibody
    • NGFIC antibody
    • PAT133 antibody
    see all

Anti-EGR4 antibody 图像

  • Anti-EGR4 antibody (ab50636) at 0.0625 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50,000 - 1/100,000 dilution.

    Predicted band size : 51 kDa
    Observed band size : 46 kDa (why is the actual band size different from the predicted?)

Anti-EGR4 antibody (ab50636)参考文献

ab50636 has not yet been referenced specifically in any publications.

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