Anti-EGF抗体[S-177] (ab18635)

概述

  • 产品名称Anti-EGF抗体[S-177]
    参阅全部 EGF 一抗
  • 描述
    小鼠单克隆抗体[S-177] to EGF
  • 特异性Does not cross react with other cytokines tested such as IL-1beta, IL-8, MCAF, TGF beta abd SAA.
  • 经测试应用适用于: Sandwich ELISA, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Purified recombinant human EGF, 6 kDa, 53 amino acid residues.

性能

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应用

Our Abpromise guarantee covers the use of ab18635 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Sandwich ELISA Use a concentration of 5 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to EGF (ab9695). For sandwich ELISA , use this antibody as Capture at 5µg/ml with ab9695 as Detection.
ELISA Use at an assay dependent dilution.

靶标

  • 功能EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
  • 组织特异性Expressed in kidney, salivary gland, cerebrum and prostate.
  • 疾病相关Hypomagnesemia 4
  • 序列相似性Contains 9 EGF-like domains.
    Contains 9 LDL-receptor class B repeats.
  • 翻译后修饰O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Beta urogastrone antibody
    • EGF antibody
    • EGF_HUMAN antibody
    • Epidermal growth factor antibody
    • HOMG4 antibody
    • OTTHUMP00000219721 antibody
    • OTTHUMP00000219722 antibody
    • Pro epidermal growth factor antibody
    • URG antibody
    • Urogastrone antibody
    see all

Anti-EGF antibody [S-177] 图像

实验方案

Anti-EGF antibody [S-177] (ab18635)参考文献

ab18635 has not yet been referenced specifically in any publications.

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