Anti-EGF抗体(Biotin) (ab84263)

概述

  • 产品名称Anti-EGF抗体(Biotin)
    参阅全部 EGF 一抗
  • 描述
    兔多克隆抗体to EGF (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>98%) recombinant human EGF

性能

应用

Our Abpromise guarantee covers the use of ab84263 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2-0.4 ng/well of recombinant human EGF.
WB Use a concentration of 0.1 - 0.2 µg/ml. Predicted molecular weight: 134 kDa.

靶标

  • 功能EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
  • 组织特异性Expressed in kidney, salivary gland, cerebrum and prostate.
  • 疾病相关Hypomagnesemia 4
  • 序列相似性Contains 9 EGF-like domains.
    Contains 9 LDL-receptor class B repeats.
  • 翻译后修饰O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Beta urogastrone antibody
    • EGF antibody
    • EGF_HUMAN antibody
    • Epidermal growth factor antibody
    • HOMG4 antibody
    • OTTHUMP00000219721 antibody
    • OTTHUMP00000219722 antibody
    • Pro epidermal growth factor antibody
    • URG antibody
    • Urogastrone antibody
    see all

Anti-EGF antibody (Biotin) (ab84263)参考文献

ab84263 has not yet been referenced specifically in any publications.

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