概述

  • 产品名称Anti-EFTUD2抗体
    参阅全部 EFTUD2 一抗
  • 描述
    兔多克隆抗体to EFTUD2
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from internal region of human EFTUD2.

  • 阳性对照
    • HUVEC and 293 cells

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab92479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
IHC-P
  • 应用说明ELISA: 1/40,000.
    IHC-P: 1/50 - 1/100.
    WB: 1/500 - 1/1000. Predicted molecular weight: 109 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP.
    • 疾病相关Defects in EFTUD2 are the cause of mandibulofacial dysostosis with microcephaly (MFDM) [MIM:610536]. A rare syndrome characterized by progressive microcephaly, midface and malar hypoplasia, micrognathia, microtia, dysplastic ears, preauricular skin tags, significant developmental delay, and speech delay. Many patients have major sequelae, including choanal atresia that results in respiratory difficulties, conductive hearing loss, and cleft palate.
    • 序列相似性Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 116 kDa antibody
      • 116 kDa U5 small nuclear ribonucleoprotein component antibody
      • EFTUD2 antibody
      • Elongation factor Tu GTP binding domain containing 2 antibody
      • Elongation factor Tu GTP-binding domain-containing protein 2 antibody
      • hSNU114 antibody
      • MFDGA antibody
      • MFDM antibody
      • SNRNP116 antibody
      • Snrp116 antibody
      • Snu114 antibody
      • SNU114 homolog antibody
      • U5 116KD antibody
      • U5 small nuclear ribonucleoprotein component antibody
      • U5 snRNP specific protein, 116 kD antibody
      • U5 snRNP specific protein, 116 kDa antibody
      • U5 snRNP-specific protein antibody
      • U5-116 kDa antibody
      • U5-116KD antibody
      • U5S1_HUMAN antibody
      see all

    Anti-EFTUD2 antibody 图像

    • All lanes : Anti-EFTUD2 antibody (ab92479) at 1/500 dilution

      Lane 1 : HUVEC cells (-peptide)
      Lane 2 : 293 cells (-peptide)
      Lane 3 : HUVEC cells (+peptide)

      Lysates/proteins at 30 µg per lane.


      Predicted band size : 109 kDa
    • Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using ab92479 A) - peptide B) + peptide

    Anti-EFTUD2 antibody (ab92479)参考文献

    ab92479 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"