The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 27 kDa.
Use a concentration of 5 µg/ml.
功能May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
组织特异性Found in lymphocytes; preferentially expressed in CD8+ cells.
序列相似性Contains 2 EF-hand domains.
细胞定位Membrane raft. In immature B-cell line WEHI231.