概述

  • 产品名称
  • 描述
    兔多克隆抗体to EFHD2
  • 特异性
    ab106667 is predicted to not cross-react with EFHD1.
  • 经测试应用
    适用于: IHC-P, ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A 16 amino acid synthetic peptide near the amino terminus of Human EFHD2 (NP_077305)

  • 阳性对照
    • Mouse brain tissue lysate and Human brain tissue.

性能

应用

Our Abpromise guarantee covers the use of ab106667 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 27 kDa.

靶标

  • 功能
    May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
  • 组织特异性
    Found in lymphocytes; preferentially expressed in CD8+ cells.
  • 序列相似性
    Contains 2 EF-hand domains.
  • 细胞定位
    Membrane raft. In immature B-cell line WEHI231.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EF hand domain containing protein 2 antibody
    • EF hand domain family, member D2 antibody
    • EF-hand domain-containing protein D2 antibody
    • EFHD 2 antibody
    • EFHD2 antibody
    • EFHD2_HUMAN antibody
    • RP3-467K16.3 antibody
    • Swiprosin 1 antibody
    • Swiprosin-1 antibody
    • SWS1 antibody
    see all

图片

  • Immunofluorescence of EFHD2 in Human brain tissue with ab106667 at 20 ug/mL.

  • Lane 1 : Anti-EFHD2 antibody (ab106667) at 1 µg/ml
    Lane 2 : Anti-EFHD2 antibody (ab106667) at 2 µg/ml

    Lane 1 : Mouse brain tissue lysate
    Lane 2 : Mouse brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 27 kDa
  • ab106667, at 5 µg/ml, staining EFHD2 in paraffin embedded Human brain tissue by immunohistochemistry.

文献

ab106667 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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