概述

  • 产品名称Anti-EFEMP2抗体
    参阅全部 EFEMP2 一抗
  • 描述
    小鼠多克隆抗体to EFEMP2
  • 特异性This antibody is reactive against mammalian transfected lysate.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length EFEMP2 protein (Human)

  • 阳性对照
    • Human kidney tissue lysate and EFEMP2 transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab67665 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/500 - 1/1000. Detects a band of approximately 60 kDa (predicted molecular weight: 49 kDa).
    Detection Antibody Pair.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 疾病相关Defects in EFEMP2 are a cause of cutis laxa autosomal recessive type 1 (ARCL1) [MIM:219100]. Hereditary cutis laxa refers to a heterogeneous group of connective tissue disorders characterized by cutaneous abnormalities and variable systemic manifestations. The most constant clinical feature is loose skin, sagging over the face and trunk. Hereditary cutis laxa is inherited in both autosomal dominant and autosomal recessive modes. ARCL1 shows the most severe phenotype and has the poorest prognosis. In addition to the skin, internal organs enriched in elastic fibers, such as the lung and arteries, are affected.
    • 序列相似性Belongs to the fibulin family.
      Contains 6 EGF-like domains.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • EFEMP 2 antibody
      • EFEMP2 antibody
      • EGF containing fibulin like extracellular matrix protein 2 antibody
      • EGF-containing fibulin-like extracellular matrix protein 2 antibody
      • FBLN 4 antibody
      • FBLN4 antibody
      • FBLN4_HUMAN antibody
      • FIBL 4 antibody
      • FIBL-4 antibody
      • FIBL4 antibody
      • Fibulin 4 antibody
      • Fibulin-4 antibody
      • MBP 1 antibody
      • MBP1 antibody
      • Mutant p53 binding protein 1 antibody
      • Protein UPH1 antibody
      • UPH 1 antibody
      • UPH1 antibody
      • UPH1 protein antibody
      see all

    Anti-EFEMP2 antibody 图像

    • Anti-EFEMP2 antibody (ab67665) at 1/500 dilution + human kidney tissue lysate at 25 µg

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 49 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)
    • All lanes : Anti-EFEMP2 antibody (ab67665) at 1/500 dilution

      Lane 1 : EFEMP2 transfected 293T cell lysate
      Lane 2 : Non transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

      Predicted band size : 49 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)

    Anti-EFEMP2 antibody (ab67665)参考文献

    ab67665 has not yet been referenced specifically in any publications.

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