• 产品名称Anti-EFEMP1抗体
    参阅全部 EFEMP1 一抗
  • 描述
    兔多克隆抗体to EFEMP1
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from an internal region of Human EFEMP1.

  • 阳性对照
    • Extracts from Rat lung cells



Our Abpromise guarantee covers the use of ab92725 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
  • 应用说明ELISA: 1/20000.
    WB: 1/500 - 1/1000. Predicted molecular weight: 55 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
    • 组织特异性In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina.
    • 疾病相关Defects in EFEMP1 are a cause of Doyne honeycomb retinal dystrophy (DHRD) [MIM:126600]; also known as malattia leventinese (MLVT) (ML). DHRD is an autosomal dominant disease characterized by yellow-white deposits known as drusen that accumulate beneath the retinal pigment epithelium.
    • 序列相似性Belongs to the fibulin family.
      Contains 6 EGF-like domains.
    • 细胞定位Secreted > extracellular space. Secreted > extracellular space > extracellular matrix. Localizes to the lamina propria underneath the olfactory epithelium.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DHRD antibody
      • Doyne honeycomb retinal degeneration antibody
      • DRAD antibody
      • EFEMP 1 antibody
      • EFEMP1 antibody
      • EGF containing fibulin like extracellular matrix protein 1 antibody
      • EGF containing fibulin like extracellular matrix protein 1 precursor antibody
      • EGF-containing fibulin-like extracellular matrix protein 1 antibody
      • Epidermal growth factor containing fibulin like extracellular matrix protein 1 antibody
      • Extracellular protein S1 5 antibody
      • Extracellular protein S1-5 antibody
      • FBLN 3 antibody
      • FBLN3 antibody
      • FBLN3_HUMAN antibody
      • FBNL antibody
      • FIBL 3 antibody
      • FIBL-3 antibody
      • FIBL3 antibody
      • Fibrillin like antibody
      • Fibrillin like protein antibody
      • Fibrillin-like protein antibody
      • FIBULIN 3 antibody
      • Fibulin-3 antibody
      • Fibulin3 antibody
      • FLJ35535 antibody
      • Heat shock 70 KD protein 1 antibody
      • MGC111353 antibody
      • MLVT antibody
      • MTLV antibody
      • S1 5 antibody
      • T16 protein antibody
      see all

    Anti-EFEMP1 antibody 图像

    • All lanes : Anti-EFEMP1 antibody (ab92725) at 1/500 dilution

      Lane 1 : extracts from Rat lung cells
      Lane 2 : extracts from Rat lung cells with immunizing peptide at 5 µg

      Lysates/proteins at 10 µg per lane.

      Predicted band size : 55 kDa

    Anti-EFEMP1 antibody (ab92725)参考文献

    ab92725 has not yet been referenced specifically in any publications.

    Product Wall

    Application Western blot
    Sample Human Cell lysate - other (Transfected HEK293 cells, conditioned medium)
    Loading amount 15 µg
    Specification Transfected HEK293 cells, conditioned medium
    Gel Running Conditions Reduced Denaturing (8% SDS-PAGE)
    Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 22°C

    Dr. Mariano Viapiano

    Verified customer

    提交于 Sep 09 2011