Anti-EEF2 (phospho T56)抗体(ab115165)

概述

  • 产品名称Anti-EEF2 (phospho T56)抗体
    参阅全部 EEF2 一抗
  • 描述
    兔多克隆抗体to EEF2 (phospho T56)
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to a region of Human EEF2 phosphorylated at Threonine 56.

  • 阳性对照
    • K562 cell extract; NIH3T3 cell extract

性能

应用

Our Abpromise guarantee covers the use of ab115165 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 95 kDa (predicted molecular weight: 95 kDa). (Colorimetric).

靶标

  • 功能Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
  • 序列相似性Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
  • 翻译后修饰Phosphorylation by EF-2 kinase completely inactivates EF-2.
    Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A, thus arresting protein synthesis.
    ISGylated.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EEF 2 antibody
    • Eef2 antibody
    • EF-2 antibody
    • EF2 antibody
    • EF2_HUMAN antibody
    • Elongation factor 2 antibody
    • Eukaryotic translation elongation factor 2 antibody
    • Polypeptidyl tRNA translocase antibody
    • SCA26 antibody
    see all

Anti-EEF2 (phospho T56) antibody 图像

  • All lanes : Anti-EEF2 (phospho T56) antibody (ab115165) at 1 µg/ml

    Lane 1 : K562 cell extract
    Lane 2 : K562 cell extract treated with Anisomycin
    Lane 3 : NIH3T3 cell extract
    Lane 4 : NIH3T3 cell extract treated with Anisomycin


    Predicted band size : 95 kDa
    Observed band size : 95 kDa

Anti-EEF2 (phospho T56) antibody (ab115165)参考文献

ab115165 has not yet been referenced specifically in any publications.

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